The University of Málaga in Spain has published a new study on Instruments of Choice for Assessment and Monitoring Diabetic Foot: A Systematic Review.
1. A Simple, Effective Indicator for Early Neuropathy
Neuropad is an adhesive cobalt‑based patch applied to the sole of the foot. It visually indicates sudomotor (sweat gland) dysfunction by changing colour—from blue to pink—within 10 minutes if sweat production is normal. This non-invasive and quick approach enables early detection of small-fibre dysfunction, even in subclinical stages of diabetic neuropathy.
2. High Sensitivity Makes It a Reliable Screening Tool
Neuropad offers excellent sensitivity. A recent study observed 89% sensitivity and 78% specificity in identifying diabetic autonomic neuropathy. This makes it highly effective for initial screening: it’s likely to catch true cases, ensuring few are inadvertently missed.
3. Detects Early Small Fibre Damage
An abnormal Neuropad result can precede detectable signs using conventional assessments like the neuropathy disability score (NDS). One study found that an abnormal patch predicted diabetic neuropathy development over five years—highlighting its utility in identifying early, otherwise unnoticed small‑fibre involvement.
4. Clinically Validated Correlations
Neuropad responses show strong correlations with clinical measures of neuropathy—such as NDS, symptom scales, temperature thresholds, and intra-epidermal nerve fibre density—indicating it reflects real underlying nerve damage. This reinforces its value as a trustworthy, clinically relevant tool.
5. Convenient, Cost-Effective, and Patient-Friendly
As a simple home-use test, Neuropad requires no specialized equipment or trained personnel. Its ease, affordability, and patient comfort make it ideal for routine screening in both clinic and community settings—ensuring broader access without significant healthcare burden.
6. A Perfect First-Step in Neuropathy Management
Neuropad delivers quick, visual insight into autonomic sweat function. Its high sensitivity ensures early detection; positive results can prompt further comprehensive testing. This fosters proactive patient care, enabling earlier intervention strategies like lifestyle adjustments, glucose control, and foot care—ultimately improving outcomes.
In summary, Neuropad stands out as a sensitive, validated, easy-to-use, and cost-effective tool for early detection of diabetic neuropathy. It empowers both patients and clinicians with rapid insights into nerve health, making it an excellent frontline screening option.